In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...
This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...
Researchers uncovered how polyamines influence cell fate by altering protein phosphorylation and alternative splicing. The ...
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal form of pancreas cancer. It's also the most common form of the ...
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Polyamines reshape protein phosphorylation to guide key cellular fate decisions
Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an ...
In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly ...
New research suggests that alternative splicing may have an even greater influence on biology than just by creating new protein isoforms. The study shows that the biggest impact of alternative ...
The Krainer lab discovered a three-oncogene circuit that helps drive the aggressive progression of pancreatic ductal ...
Researchers at CSH Laboratory identified an oncogenic SRSF1–AURKA–MYC circuit driving pancreatic ductal adenocarcinoma.
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