When the team knocked out the P2Y2 receptor in drug-resistant cancer cells, it led to an almost complete loss of the mutant EGFR protein.

The field of regulated cell death has undergone a transformative shift with the discovery of novel modalities beyond apoptosis, such as ferroptosis, which ...

Cancer cell biology unravels the molecular and cellular underpinnings of tumour formation, progression and metastasis. At its core, cancer arises as a result of dysregulated cell cycle control, ...

A team of Canadian scientists has uncovered a new way to slow the growth of glioblastoma, the most aggressive and currently ...

Researchers have uncovered a stealthy way pancreatic cancer disarms the immune system, using tiny molecular messengers to ...

MYC‑driven tumors silence innate immune alarms by clearing R‑loop–derived signals, exposing a new therapeutic angle for targeting MYC without broad inhibition.

Ubiquitination is a crucial post-translational modification process where the small protein ubiquitin is attached to target proteins, marking them for degradation or altering their function. This ...

When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This ...

Of all the types of breast cancer, triple negative breast cancer (TNBC) is the most aggressive and lacks specific therapies.

The Undergraduate Cancer Biology Society (UCBS) was started in 2022 with inaugural President Sarah Elimam. Now our third year as a UAB Registered Student Organization, UCBS is excited to continue its ...

Researchers have developed a modified antibody whose role is to activate an important protein of the immune system, CD40.