In a new study, researchers compare the transcriptomic profiles of recently reported human embryo stage 8-cell-like cells with human embryos The onset of embryo-specific gene transcription, also known ...

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The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some ...

Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...