In July 2022, the World Health Organization (WHO) announced that monkeypox was a public health emergency of international concern. And, as of early December 2022, more than 82,000 human monkeypox ...

Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus. The ...

Study uncovers key insights about how a new class of antiviral drugs works. Cryo-EM images showed the drugs bound to herpes simplex virus (HSV) protein at nearly atomic detail, while optical tweezers ...

Nipah virus is a zoonotic virus harbored by fruit bats. It can be transmitted to pigs and humans, infect people through contaminated food, and can travel directly from person to person via droplets.

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has ...

For the first time, researchers from the Max Planck Institute (MPI) for Multidisciplinary Sciences and the University Medical ...

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins. Scientists ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...