Matrix metalloproteinases (MMPs) are a family of zinc-containing endopeptidases capable of degrading the extracellular matrix (ECM). Matrix degradation occurs during tissue remodeling and inflammatory ...

Background Tendinopathy commonly occurs in tendons with large in vivo loading demands like the Achilles tendon (AT) and supraspinatus tendon (SST). In addition to differences in their local anatomic ...

This is a preview. Log in through your library . Abstract Extracellular matrix (ECM) fragments or cryptic sites unmasked by proteinases have been postulated to affect tissue remodeling and cancer ...

Introduction The reason women sustain more soft tissue injuries than men is still unknown2, yet sex differences in ligament injuries, especially ACL injuries and associated biomechanical differences ...

The regulation and remodeling of the tumor microenvironment (TME) are closely associated with how cancers typically progress and metastasize. The extracellular matrix (ECM) is an intricate network of ...