WFXG

FAST III trial demonstrates non-inferiority of CAAS vFFR to invasive wire-based FFR

FAST III was initiated five years ago to evaluate whether revascularization guided by angiography–based FFR using CAAS vFFR (vessel Fractional Flow Reserve) delivers therapeutic outcomes comparable to ...
MedPage Today on MSN

Active Surveillance for DCIS Moves Closer to Standard Option but 'Not Quite There'

Large randomized trial makes case for non-inferiority versus surgery; smaller study falls ...
MedPage Today on MSN

Watchman LAA occluder bounces back as alternative to OAC in CHAMPION-AF

Study suggests a path forward for device therapy, though caveats are plenty ...

Landmark ALL-RISE® Trial Results Presented at ACC.26: CathWorks FFRangio Demonstrates Similar Clinical Outcomes to Invasive Wire-based Physiology Assessment

Today at the American College of Cardiology's Annual Scientific Session (ACC.26) taking place in New Orleans, Louisiana, Dr. Ajay J. Kirtane from New York-Presbyterian/Columbia University Irving ...
Medscape

Ultrahypofractionated Radiotherapy Shows Non-Inferiority to Conventional Care in Long-Term Prostate Cancer Outcomes

Ultrahypofractionated radiotherapy demonstrated non-inferiority to conventional fractionation with higher 10-year failure-free survival with similar toxicity profiles in patients with intermediate- or ...
The Lancet

Coronary revascularisation before TAVI

Coronary artery disease frequently accompanies severe aortic stenosis and is identified in up to half of patients referred for transcatheter aortic valve implantation (TAVI).1 Yet the optimal ...
Nature

Non-Inferiority Trials in Three-Arm Clinical Studies

Non-inferiority trials have become an essential instrument in clinical research, particularly when the goal is to demonstrate that an experimental treatment is not unacceptably worse than an ...