Nucleotide excision repair (NER) is a major conserved DNA repair pathway, which repairs various types of damage in the genome, such as those induced by ultraviolet light and environmental agents.

Hailin Wang, Meiling Lu, Moon-Shong Tang, Bennett van Houten, J. B. Alexander Ross, Michael Weinfeld, X. Chris Le, Philip C. Hanawalt Proceedings of the National ...

The excision repair cross-complementation group 1 (ERCC1) protein is a potential prognostic biomarker of the efficacy of cisplatin-based chemotherapy in non–small-cell lung cancer (NSCLC). Although ...

Maintaining the stability of the genome is essential for all organisms, and it is not surprising that damage to DNA has been proposed as an explanation for multiple chronic diseases. 1–5 Conserving a ...

Nucleotide excision repair is a process that repairs damage to one strand of the DNA, particularly from UV irradiation, which distorts the DNA helix. The DNA flanking the damage site is cleaved to ...

Damage to your DNA is unavoidable. Every day our cells are bombarded by gene-splitting UV radiation or chemical carcinogens. Regular water inside our bodies can cause DNA damage. DNA damage is as ...

Prognostic role of androgen receptor expression in triple-negative breast cancer. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract does not include a full text ...

Aziz Sancar grew up as a farm boy in a small town in Turkey. He was a bright child and attended medical school. He returned to his hometown and practiced medicine for a few years. But even in his ...