Figure 1: Generation of K14-CAP1/Prss8 transgenic mice. Figure 2: Phenotype of K14-CAP1/Prss8 transgenic mice. Figure 3: Altered protein and lipid composition in K14-CAP1/Prss8 epidermis. To test the ...
Our species is defined by a long list of cultural and genetic traits that set us apart from our ancient counterparts. New ...
Domain Therapeutics SA has nominated PAR2 antagonist DT-9046 as a drug candidate with potential to treat various inflammatory diseases, including atopic dermatitis, inflammatory bowel disease and ...
Domain Therapeutics SA has prepared and tested new azine-based compounds acting as proteinase-activated receptor 2 (F2RL1; PAR2) inhibitors reported to be useful for the treatment of allergy, ...
STRASBOURG, France, MONTREAL, BOSTON, March 20, 2025 /PRNewswire/ -- Domain Therapeutics ("Domain" or "the Company"), the GPCR experts harnessing deep receptor biology to develop breakthrough ...
Tissue factor (TF) is a transmembrane glycoprotein that localizes the coagulation serine protease factor VII/VIIa (FVII/VIIa) to the cell surface. The primary function of TF is to activate the ...