The initiation of viral RNA synthesis has evolved to take place by a wide variety of mechanisms, broadly categorized between primer-independent or primer-dependent. Considerable variation is observed ...

The Wyss Institute for Biologically Inspired Engineering at Harvard University is partnering with Northpond Labs to launch the RNA synthesis company EnPlusOne Biosciences (EnPlusOne Bio). EnPlusOne ...

The cellular replicative DNA polymerases cannot initiate DNA synthesis without a priming 3′ OH. During DNA replication, this is supplied in the context of a short RNA primer molecule synthesized by ...

The number of people using RNA-based therapeutics is set to increase substantially as new drugs reach the market, and companies are looking for ways to scale up RNA production. In September, a team ...

A new paper published in Nature Biotechnology this week titled, “Template-independent enzymatic synthesis of RNA oligonucleotides,” provides details of a method for synthesizing single-stranded RNA ...

EnPlusOne Biosciences, Inc., a biotechnology company harnessing the power of enzymes to synthesize RNA oligonucleotides, today formally launched with $12 million in seed financing. The round was led ...

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...

VIENNA, AUSTRIA—Ribonucleic acid (RNA) is, along with DNA and protein, one of the three primary biological macromolecules and was probably the first to arise in early life forms. In the “RNA ...