Laboratory tests of a novel serotonin-binding compound have revealed an unexpected disconnect between receptor activation and ...

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

When a highly pathogenic strain of H5N1 influenza virus emerged in US dairy cattle in March, scientists around the world had a slew of questions about the virus’s characteristics. In a new paper ...

Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets. After earning ...

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely ...

"To provide direct evidence for binding of the molecule at different pockets of the receptor, we have developed a new assay, which enables us to measure the binding specifically at the extracellular ...

Scientists have identified a promising target for treatment of a devasting autoimmune disease affecting the brain.

A new multi-pronged antibody design could help immune cells receive stronger activation signals against cancer. Researchers ...

Scientists have discovered that H5N1, the strain of highly pathogenic avian influenza virus currently spreading in U.S. dairy cows, only needs a single mutation to readily latch on to human cells ...