The interrupted non-coding regions in pre-mRNAs, termed “introns,” are excised by “splicing” to generate mature coding mRNAs that are translated into proteins. As human pre-mRNA introns vary in length ...

In vertebrates, large exons often skip splicing events and are evolutionarily conserved. Scientists have recently identified the mechanism behind regulated splicing of large constitutive exons which ...

What kills most people who die from cancer is not the initial tumor. It’s the intolerable disease burden on the body that arises when tumor cells continually expand their numbers after spreading to ...

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor Protein-coding genes carry the blueprint for protein production. In higher ...

Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor, new research finds. The interrupted non-coding regions in pre-mRNAs, termed ...

Human introns have extensively varying lengths. Previously, only U2AF-dependent splicing was known. Researchers from Fujita Health University now show that splicing in a subset of human short introns ...