A recombinant form of human ADAMTS13 approved for a different condition helped to save the life of a young mother with immune thrombotic thrombocytopenic purpura. A team led by investigators from ...

Caplacizumab is a von Willebrand factor (vWF)-directed antibody fragment designed to inhibit the interaction between vWF and platelets.

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

Blood clotting disorders can be inherited or acquired and lead to either excessive bleeding or too much clotting.

Thrombocytopenia is an atypically low platelet count. Acquired thrombocytopenia is caused by conditions that develop throughout your life instead of genes inherited from birth. Acquired ...