Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Leading cancer experts at the University of Birmingham have solved a long-standing question of how various types of mutations in just one gene cause different types of diseases. A team of scientists ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 80, No. 6, [Part 1: Biological Sciences] (Mar. 15, 1983), pp. 1660-1664 (5 pages) ...

EGFR-positive lung cancer is a type of non-small cell lung cancer (NSCLC). It can cause symptoms such as breathing problems and hoarseness. Therapy that targets the mutation, such as EGFR inhibitors, ...

Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that breaks down the amino acid homocysteine. If the MTHFR gene that codes for this enzyme mutates, it may contribute to health issues, such as ...

Molecular biology is an ever-changing field, and most significant developments have happened because of changes in plasmid DNA sequencing. A plasmid, a circular and small double-stranded DNA entity ...

This is a preview. Log in through your library . Abstract A strong mutator effect has been observed in Escherichia coli K-12 strains mutated in the bglY gene (27 min). The frequency of point mutations ...