CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Along with the TCR, the CD8 co-receptor plays a role in T cell …

Dec 23, 2024 · Find out what you need to know about the CD4:CD8 ratio test. Learn why your doctor asks for it, what information they get from it, and what it means for you.

Nov 1, 2023 · This review highlights recent advancements in our understanding of CD8 T-cell subsets and the contributions of these cells to various disease pathologies.

Dec 15, 2025 · The CD4/CD8 ratio is one of the blood tests used to monitor your immune system if you have human immunodeficiency virus (HIV). It compares the proportion of CD4 T cells to …

CD8+ (cytotoxic) T cells, like CD4+ Helper T cells, are generated in the thymus and express the T-cell receptor. However, rather than the CD4 molecule, cytotoxic T cells express a dimeric co …

Expressed on the surface of CD8 + T cells, the CD8 co-receptor is a key component of the T cells that contributes to antigen recognition, immune cell maturation, and immune cell signaling.

Aug 24, 2023 · Mutations in alpha chain cause CD8 deficiency, with recurrent bacterial infections (J Clin Invest 2001;108:117) Accumulate in advanced atherosclerotic plaques (Hum Pathol …