The role of immune checkpoint molecules in cancers - Frontiers
1 day ago · In contrast, active immunotherapy stimulates the patient’s own immune system to attack cancer cells, for example, through vaccination or chimeric antigen receptor T cell …
Cancer cells hijack immune mitochondria to evade attacks and …
13 hours ago · Immune checkpoints are proteins that mark cells so immune cells do not attack normal cells. Cancer cells that hijacked mitochondria disguised themselves with the immune …
From immune evasion to activation: A new cancer vaccine strategy
1 day ago · A central obstacle is immune evasion: tumor cells suppress immune responses by expressing checkpoint proteins such as PD-L1 while failing to present sufficient antigenic …
How Cancer Tumors Hijack the Body’s Defense System
May 10, 2024 · Authors note that tumors likely employ a variety of strategies to evade immune detection. But the discovery could lead to a new approach for targeted cancer therapies.
Cancer might evade immune defences by stealing mitochondria
1 day ago · Hijacking the energy-producing organelles from immune cells seems to help tumours in mice to infiltrate lymph nodes.
Linavonkibart demonstrates early potential to overcome resistance …
2 days ago · According to a Phase I study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, the novel monoclonal antibody …
CD300a: An Innate Immune Checkpoint Shaping Tumor …
Nov 27, 2025 · Recent studies suggest that tumor cells may hijack CD300a-associated pathways to establish an immunosuppressive microenvironment that facilitates immune evasion, tumor …
How Does Cancer Evade the Immune System? - Biology Insights
Dec 16, 2025 · Even if a T-cell recognizes a cancer cell, the tumor employs a second strategy to shut down the immune attack through molecular signaling. This involves exploiting natural …
Unlocking NK cells: Novel checkpoint targets revolutionize cancer ...
Aug 5, 2025 · A comprehensive analysis published in Reserch illuminates how cancer cells hijack immune checkpoints on natural killer (NK) cells to disable the body’s frontline defense system.
The Role of Immune Checkpoint Inhibitors in Cancer Therapy
Mar 13, 2025 · However, tumor cells have developed sophisticated ways to evade detection, including hijacking the immune system’s brake mechanism, known as immune checkpoints.