Despite this compelling and consistent literature for the use of TLR agonists + CD40 Ab in preclinical vaccine studies, this combination has yet to be evaluated in humans.
Since pDC and mDC synergize in the generation of antigen-specific T-cells, we propose to use a TLR agonist, R848, which is capable of activating both pDC and mDC through TLR 7 and 8, …
Glossary Terms | ClinicalTrials.gov
ClinicalTrials.gov Glossary TermsInformation required by the Food and Drug Administration Amendments Act of 2007. In general, this is a description of any agreement between the …
SAS SC SD SE SF-36 sLEPR SOC SUSAR TEAE TF TG TLR TP1 TP2 ULN WBC WOCBP Weekly Red blood cell Risk-Based Quality Monitoring Regeneron Pharmaceuticals, Inc. …
PERIPHERAL BLOOD MOLECULAR STAGING OF BREAST CANCER
Known allergy, or history of serious adverse reaction to vaccines or TLR agonists such as anaphylaxis, hives, or respiratory difficulty.
A Prospective Multi-Centre Clinical Investigation of the
TLR (Target Lesion Revascularization): Any repeat treatment of the stented segment including 5 mm proximal and 5 mm distal from the edge of the stent.
Document Title
Defined as cardiac death, target vessel myocardial infarction (Q wave and non-Q wave), or clinically driven target lesion revascularization (TLR) by percutaneous or surgical methods.
To safeguard the immune response, viruses can be sensed by many partially redundant, but also distinct classes of innate immune receptors, such as the nucleic-acid sensors, MDA-5 and RIG …
Pro-inflammatory cytokines in whole blood with and without in vitro TLR stimulation IFN , IFN , IL-6, TNF , and IL-1 in supernatant of stimulated and unstimulated whole blood cells
A PHASE III, RANDOMIZED, DOUBLE-BLIND, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF REMDESIVIR PLUS TOCILIZUMAB COMPARED WITH …